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Mol Cell Biol. 1990 April; 10(4): 1793-1798

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.

G T Drivas, A Shih, E Coutavas, M G Rush and P D'Eustachio

Department of Biochemistry, New York University School of Medicine, New York 10016.

ABSTRACT

A mixed-oligonucleotide probe was used to identify four ras-like coding sequences in a human teratocarcinoma cDNA library. Two of these sequences resembled the rho genes, one was closely related to H-, K-, and N-ras, and one shared only the four sequence domains that define the ras gene superfamily. Homologs of the four genes were found in genomic DNA from a variety of mammals and from chicken. The genes were transcriptionally active in a range of human cell types.

Mol Cell Biol. 1990 April; 10(4): 1793-1798




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