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Mol Cell Biol. 1990 August; 10(8): 4384-4388

A helix-loop-helix protein related to the immunoglobulin E box-binding proteins.

C S Carr and P A Sharp

Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139.

ABSTRACT

A human cDNA encoding a novel protein in the helix-loop-helix family has been isolated by screening a bacteriophage expression library with a probe containing the binding site for major late transcription factor. The protein encoded by this cDNA, TFEB, probably recognizes E-box sequences in the heavy-chain immunoglobulin enhancer.

Mol Cell Biol. 1990 August; 10(8): 4384-4388




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