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Mol Cell Biol. 1991 March; 11(3): 1765-1769

Common factor 1 is a transcriptional activator which binds in the c-myc promoter, the skeletal alpha-actin promoter, and the immunoglobulin heavy-chain enhancer.

K J Riggs, K T Merrell, G Wilson and K Calame

Department of Biological Chemistry, University of California Los Angeles 90024.

ABSTRACT

Ubiquitously expressed transcription factors play an integral role in establishing and regulating patterns of gene transcription. Common factor 1 (CF1) is a ubiquitously expressed DNA-binding protein previously identified in our laboratory. We show here that CF1 recognizes sites in several diverse transcription elements, and we demonstrate the ability of the c-myc CF1 site to activate transcription of a basal promoter in both B cells and fibroblasts.

Mol Cell Biol. 1991 March; 11(3): 1765-1769




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