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Mol Cell Biol. 1984 June; 4(6): 1175-1178

Differential phosphorylation of MAP-2 stimulated by calcium-calmodulin and cyclic AMP.

H Schulman

ABSTRACT

Comparison of cyclic AMP- and calcium-dependent phosphorylation in rat brain cytosol reveals MAP-2 to be a common endogenous substrate. Examination of limited protease digestion patterns indicates that the two kinases phosphorylate MAP-2 at distinct sites and suggests that such phosphorylation may have differential effects on MAP-2 function.


Mol Cell Biol. 1984 June; 4(6): 1175-1178




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