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Mol Cell Biol. 1984 June; 4(6): 1186-1188

Phosphorylation of histones in cells treated with hypertonic and acidic media.

P Pantazis, M H West and W M Bonner

ABSTRACT

Factors in the extracellular environment, specifically hypertonic or acidic growth media, are shown to alter the modification of histones in several cell lines. For histone 2A, changes in modification were visible in the mass pattern and were found to be primarily changes in phosphorylation. The increased modification of the core histones was quickly reversed when cells were returned to normal medium.

Mol Cell Biol. 1984 June; 4(6): 1186-1188






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