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Mol Cell Biol. 1987 April; 7(4): 1530-1534

Heat-inducible human factor that binds to a human hsp70 promoter.

R E Kingston, T J Schuetz and Z Larin

ABSTRACT

A factor found in nuclear extracts of human cells bound to the heat shock element of a human heat shock protein 70 gene. The level of this factor was significantly increased after heat shock. This induction was rapid and was not blocked by cycloheximide, suggesting that an initial event in the response of a human cell to heat is the activation of a preexisting regulatory factor.

Mol Cell Biol. 1987 April; 7(4): 1530-1534




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