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Mol Cell Biol. 1988 December; 8(12): 5541-5544

Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries.

S Kornbluth, K E Paulson and H Hanafusa

Rockefeller University, New York, New York 10021-6399.

ABSTRACT

In an attempt to clone protein tyrosine kinases, antiphosphotyrosine antibodies were used to screen lambda gt11 cDNA expression libraries. By this method, a 2.5-kilobase cDNA encoding a novel tyrosine kinase was isolated from a mouse liver cDNA library. This new gene is most closely related to the receptor tyrosine kinases ret, fms, and kit.


Mol Cell Biol. 1988 December; 8(12): 5541-5544




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