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Mol Cell Biol. 1989 December; 9(12): 5726-5732

Sequence and structure of the Drosophila melanogaster ovarian tumor gene and generation of an antibody specific for the ovarian tumor protein.

W R Steinhauer, R C Walsh and L J Kalfayan

Department of Biochemistry, University of North Carolina, Chapel Hill 27599.

ABSTRACT

Sequencing cDNA and genomic DNA from the ovarian tumor gene revealed a gene with seven introns spanning 4.5 kilobases. The proline-rich, hydrophilic otu protein is novel. An antibody prepared to a beta-gal-otu fusion protein recognized a 110-kilodalton ovarian protein which was altered in the ovaries of otu gene mutants.

Mol Cell Biol. 1989 December; 9(12): 5726-5732




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