Notch Activation Induces Endothelial Cell Cycle Arrest and Participates in Contact Inhibition: Role of p21Cip1 Repression
Mol. Cell. Biol. Noseda et al.
24: 8813
Supplemental materials
Files in this Data Supplement:
- Figs. S1 - S4 -
Figure S1. Expression of Notch4IC, Notch1IC, and Notch4IC-ER.
Figure S2. Notch 4IC and Notch1IC inhibit S-phase entry in HAEC.
Figure S3. Relative expression of cdk4, cyclin D, and p16INK4a in HUVEC-vector and Notch4IC-ER following serum stimulation.
Figure S4. Densitometric analysis shows statistically significant Notch-dependent downregulation of p21Cip1 following endothelial cell-cell interactions.
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