
Transforming Growth Factor ß (TGF-ß)-Smad Target Gene Protein Tyrosine Phosphatase Receptor Type Kappa Is Required for TGF-ß Function
Mol. Cell. Biol. Wang et al.
25: 4703
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Files in this Data Supplement:
- Supplemental file 1
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Supplemental Fig. S1.(RPTP[Greek kappa] expression in MMTV-Neo x MMTV-HA-Alk5T204D bigenic and MMTV-Neu transgenic mouse tumors) and S2 (Knock-down of RPTP[Greek kappa] leads to altered morphology and cell death in MCF10A cells).
Zipped Tif document, 2.4MB.
- Supplemental file 2
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Supplemental Fig. S3 (Expression of RPTP[Greek kappa] has no effect on TGF
-induced transcriptional reporter activity) and S4 (RPTP[Greek kappa] reduces EGFR phosphorylation and proliferation in A431I cells).
Zipped Tif document, 1.3MB.
- Supplemental file 3
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Supplemental Fig. S5 (Colocalization of RPTP[Greek kappa] and vinculin at focal adhesions) and S6 (Overexpression of RPTP[Greek kappa] activates Src in MCF7 cells).
Zipped Tif document, 503K.