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Leukemia-Associated Mutations within the NOTCH1 Heterodimerization Domain Fall into at Least Two Distinct Mechanistic Classes
Mol. Cell. Biol. Malecki et al. 26: 4642

Supplemental material

Files in this Data Supplement:

  • Supplemental file 1 - Fig. S1 (HD domain mutations effect on sensitivity to ligand), S2 (DAPT effect on stimulatory effects of HD domain mutations in full-length NOTCH1), S3 (Serial dilutions of sHD immunoprecipitates), and S4 (Representative repeat evaluation of the P12 mutation in the urea sensitivity assay)
    PDF document, 4.5MB.



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