Files in this Data Supplement:

• Supplemental file 1 - Legends for Fig. S1 to S4 and Videos S1 to S8
  MS Word document, 38K.
• Supplemental file 2 - Fig. S1 (Morphology and cytoskeleton organization of mDia1 RNAi cells), S2 (Rho-dependent, ROCK-independent SDF-1α -directed migration of rat C6 glioma cells), S3 (Impaired MT stabilization in mDia1-depleted cells), and S4 (Effects of mDia1 RNAi with siRNA A6 on migration, MTOC orientation, and adhesion turnover of C6 glioma cells)
  Zipped TIF documents, 7MB.
• Supplemental file 3 - Videos S1 and S2 (Suppression of glioma cell migration by mDia1 depletion in a Dunn chamber for control S1 and mDia1 S2 RNAi), S3 and S4 (Impaired polarization of active Rac in mDia1 RNAi cells for control S3 and mDia1 S4 RNAi), S5 and S6 (Impaired polarization of active Cdc42 in mDia1 RNAi cells for control S5 and mDia1 S6 RNAi), and S7 and S8 (Impaired turnover of focal adhesions in mDia1 RNAi cells for control S7 and mDia1S8 RNAi)
  Zipped QuickTime videos, 3.1MB.