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Skeletal Muscle-Selective Knockout of LKB1 Increases Insulin Sensitivity, Improves Glucose Homeostasis, and Decreases TRB3
Mol. Cell. Biol. Koh et al. 26: 8217

Supplemental material

Files in this Data Supplement:

  • Supplemental file 1 - Fig. S1 (AMPKα2 activity is ablated in basal and AICAR- and contraction-stimulated skeletal muscle from MLKB1KO mice), S2 (AMPK phosphorylation and ACC phosphorylation are altered in AICAR- and contraction-stimulated skeletal muscle from MLKB1KO mice), S3 (AMPK subunit protein expression is increased in MLKB1KO mice), S4 (Enzyme activities of the AMPK-related kinases, MARK2/3 and MARK4), and S5 (Effect of TRB3 on insulin-stimulated Akt Thr308 phosphorylation was dose dependent)
    Zipped PowerPoint document, 532K.
  • Supplemental file 2 - Legends for Fig. S1 to S5
    MS Word document, 6K.
  • Supplemental file 3 - Table S1 (Metabolic parameters of LKB1MKO mice in fed and fasted status)
    MS Word document, 33K.




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