The KAP1 Corepressor Functions To Coordinate the Assembly of De Novo HP1-Demarcated Microenvironments of Heterochromatin Required for KRAB Zinc Finger Protein-Mediated Transcriptional Repression
Mol. Cell. Biol. Sripathy et al.
26: 8623
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Fig. S1 (Stable depletion of KAP1 in HEK293 cells), S2 (Direct tethering of KAP1 to DNA is sufficient to represses transcription), S3 (Characterization of cell lines with a chromatinized 5XGAL4-TK-luciferase transgene), S4 (Hormone-dependent repression of chromatinized luciferase transgenes by ERHBDTM-GAL4-fused repressor proteins), S5 (Hormone-dependent KRAB repression is dependent on KAP1), S6 (KRAB mediated repression of a chromatin template is independent of TIF1α and TIF1γ), S7 (Expression of the KAP1 repression machinery), S8 (Hormone-dependent repression mediated by KAP1 involves hypoacetylation of histone H3 K9 of transgenic reporter), S9 (ChIP analysis of hormone-dependent changes in RNA polymerase II, histone occupancy, and histone modifications at promoter sequences of an integrated transgene bound by ERHBDTM-GAL4-KAP1), and S10 (Transient knockdown of HP1β expression and its effect on KRAB-mediated repression)
Zipped PDF document, 3MB.
- Supplemental file 2
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Legends to Fig. S1 to S10
MS Word document, 33K.
