
SUMO-1-Dependent Allosteric Regulation of Thymine DNA Glycosylase Alters Subnuclear Localization and CBP/p300 Recruitment
Mol. Cell. Biol. Mohan et al.
27: 229
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Fig. S1 (SUMO-1 binding does not interfere with DNA binding) and S2 (DNA glycosylase activity of in vitro-translated TDG and SUMO-binding motif point, mutants)
Zipped PDF document, 126K.
- Supplemental file 2
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Fig. S3 (SUMO-1 binding activity of MCF-7-expressed TDG resides in amino- and carboxy-terminal motifs) and S4 (SUMO binding motif mutants bind CBP in vitro)
Zipped PDF document, 94K.
- Supplemental file 3
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Fig. S5 (Sumoylation sites in CBP are not required for activation by TDG) and S6 (Sumoylated TDG possesses robust G:U processing activity)
Zipped PDF document, 75K.