Degradation of Mcl-1 by ß-TrCP Mediates Glycogen Synthase Kinase 3-Induced Tumor Suppression and Chemosensitization
Mol. Cell. Biol. Ding et al.
27: 4006
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Fig. S1 (MEF cells possess GSK-3β kinase activity), S2 (GSK-3β was not associated with Mcl-1 and cannot downregulate Mcl-1), S3 (GSK-3 phosphorylated Mcl-1), S4 (β-TrCP downregulation led to Mcl-1 stabilization), S5 (Treatment with UV and staurosporine leads to GSK-3β activation and Mcl-1 downregulation), and S6 (Tumor volumes after liposome complex injection)
Zipped PDF document, 139K.
- Supplemental file 2
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Legends to Fig. S1 to S6
MS Word document, 30K.
