Files in this Data Supplement:

• Supplemental file 1 - Legends to Fig. S1 to S4
  MS Word document, 27K.
• Supplemental file 2 - Fig. S1 (Comparison of cyclin D1-CDK-CKI complexes in young and senescent HDFs), S2 (Extension of HDF lifespan by wild-type and mutant versions of CDK4 and CDK6), S3 (CDK4 and CDK6 can extend the lifespan of p16^INK4a-deficient HDFs), and S4 (Polycomb-mediated repression of p16^INK4a does not prevent lifespan extension by CDK4)
  Zipped PowerPoint document, 6.5MB.