Files in this Data Supplement:

• Supplemental file 1 - Supplemental text, legends to Fig. S1 to S4, and Tables S1 (Polypeptides identified by mass spectrometry in Bmi-1 and Mel-18 TAP), S2 and S3 (GeneGO pathway S2 and transcription factor S3 categorization of upregulated genes), and S4 (Upregulated genes in Bmi-1 and Mel-18 shRNA-expressing DAOY cells)
  MS Word document, 493K.
• Supplemental file 2 - Fig. S1 (Additional shRNAs targeting Bmi-1 and Mel-18 inhibit proliferation of DAOY cells), S2 (Depletion of Bmi-1 and Mel-18 by shRNA suppresses growth of MCF7 cells), S3 (shRNA-mediated downregulation of Bmi-1 and Mel-18 is not indiscriminately cytotoxic), and S4 (Q-RT-PCR confirmation of differentially expressed genes identified by microarray analysis)
  Zipped PowerPoint document, 4.6MB.