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Fer-Mediated Cortactin Phosphorylation Is Associated with Efficient Fibroblast Migration and Is Dependent on Reactive Oxygen Species Generation during Integrin-Mediated Cell Adhesion
Mol. Cell. Biol. Sangrar et al. 27: 6140

Supplemental material

Files in this Data Supplement:

  • Supplemental file 1 - Legends to Fig. S1 to S6 and Movies S1 to S3
    MS Word document, 34K.
  • Supplemental file 2 - Fig. S1 (Fer is activated by H2O2 in a variety of cell types)
    Zipped TIF document, 642K.
  • Supplemental file 3 - Fig. S2 (H2O2 strongly induced Ctn phosphorylation at Y421 and Y466)
    Zipped TIF document, 224K.
  • Supplemental file 4 - Fig. S3 (Integrin engagement-induced phosphorylation of paxillin and p130Cas in ferDR/DR MEF)
    Zipped TIF document, 559K.
  • Supplemental file 5 - Fig. S4 (Fer rescue expression levels)
    Zipped TIF document, 409K.
  • Supplemental file 6 - Fig. S5 (Fer autophosphorylation and Ctn phosphorylation were not stimulated by H2O2 treatment in vitro)
    Zipped TIF document, 434K.
  • Supplemental file 7 - Fig. S6 (Fn-induced tyrosine phosphorylation of Fer in the presence of NAC, Tiron, and DPI)
    Zipped TIF document, 149K.
  • Supplemental file 8 - Movie S1 (Migration of a monolayer of wt MEF across a scrape wound)
    Zipped QuickTime video, 8MB.
  • Supplemental file 9 - Movie S2 (Migration of a monolayer of fer-deficient MEF across a scrape wound)
    Zipped QuickTime video, 8.8MB.
  • Supplemental file 10 - Movie S3 (Migration of a monolayer of MEF rescued by DsRed-Fer)
    Zipped QuickTime video, 10.4MB.




This Article
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