Files in this Data Supplement:

• Supplemental file 1 - Legends to Fig. S1 to S6
  MS Word document, 28K.
• Supplemental file 2 - Fig. S1 (Histological characterization of bone metastasis formed by DU145Ras^V12G37 cells), S2 (Osteoclastogenic activity in DU145 cells expressing EV control, Ras^V12, or different Ras effector mutants), S3 (Noninvasive bioluminescence imaging to monitor the distribution and development of metastasis over time), S4 (Tumorigenic growth rate of DU145Ras^V12G37 cells expressing EV control or shRNAs against RalA and RalB), S5 (Luciferase activity levels and tumorigenic growth rate of PC3 cells), and S6 (Knockdown of neither RalA nor RalB affects the bone metastatic behavior of MDA-MB-231 cells)
  Zipped PDF document, 1.4MB.