Files in this Data Supplement:

• Supplemental file 1 - Legends to Fig. S1 to S4 and Tables S1 and S2
  MS Word document, 31K.
• Supplemental file 2 - Fig. S1 (Ratio of the roX-FF to the control R plasmid)
  Zipped TIF document, 170K.
• Supplemental file 3 - Fig. S2 (Firefly luciferase expression in roX-FF as a function of tTA concentration)
  Zipped TIF document, 158K.
• Supplemental file 4 - Fig. S3 (Simultaneous depletion of dSet2 and Mes-4)
  Zipped TIF document, 202K.
• Supplemental file 5 - Fig. S4 (Chromatin immunoprecipitation with H3K36me3 antibody)
  Zipped TIF document, 53K.
• Supplemental file 6 - Table S1 (Primers used)
  Zipped EPS document, 376K.
• Supplemental file 7 - Table S2 (Knockdown levels following dsRNA treatment)
  Zipped TIF document, 384K.