Loss of Emi1-Dependent Anaphase-Promoting Complex/Cyclosome Inhibition Deregulates E2F Target Expression and Elicits DNA Damage-Induced Senescence
Mol. Cell. Biol. Verschuren et al.
27: 7955
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
-
Legends to Fig. S1 to S6 and supplemental text
MS Word document, 38K.
- Supplemental file 2
-
Fig. S1 (Validation of rabbit anti-mouse Emi1 antibody), S2 (Cell cycle arrest upon etoposide treatment), S3 (Cell cycle analysis upon Emi1 knockdown), S4 (Further characterization of the Emi1 depletion-associated senescence phenotype), S5 (Knockdown of Evi5 does not trigger DNA damage), and S6 (Knockdown of Pin1 does not elicit extensive cellular senescence)
Zipped PDF document, 4MB.
