Files in this Data Supplement:

• Supplemental file 1 - Supplemental text and Fig. S1 (SIRT3 is exclusively mitochondrial in mice exposed to metabolic challenge), S2 (SIRT3-deficient mice are viable and born at a Mendelian ratio), S3 (Generation of SIRT5-deficient mice), S4 (Identification of GDH by LC-MS), S5 (LC-MS identification of acetylated lysine residues in GDH), S6 (Amino acid alignment of bovine and murine GDH), S7 (No histologic defects in SIRT3-deficient animals), S8 (Normal adaptive thermogenic function in SIRT3 KO mice), and S9 (Unaltered α-ketoglutarate levels in tissues from SIRT3 KO mice)
  Zipped PDF document, 5.5MB.
• Supplemental file 2 - Table S1 (GDH peptides identified by LC-MS)
  Zipped Excel document, 43K.