Files in this Data Supplement:

• Supplemental file 1 - Fig. S1 (Chk1 depletion induced Puma and Noxa expression), S2 (Phosphorylation of Chk1 at Ser317 and Ser345 under unperturbed cell cycle), S3 (Centrosomal association of wild-type Chk1, but not S345A or S317A, was enhanced by DNA damage induced by UV treatment), and S4 (Wild-type Chk1-PACT, but not K38M-PACT, was colocalized with phospho-Cdk1 at Tyr15)
  MS PowerPoint document, 4.6 MB.