A Single-Nucleotide Polymorphism in a Half-Binding Site Creates p53 and Estrogen Receptor Control of Vascular Endothelial Growth Factor Receptor 1
Mol. Cell. Biol. Menendez et al.
27: 2590
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Supplemental text and Fig. S1 (Luciferase expression in SaOS2 using the ERE/p53RE-T Flt1 chimera), S2 (ERβ cooperates with p53 to induce transcription from the human Flt1-T promoter allele), S3 (Transcriptional cooperation between p53 and ERβ at the human Flt1-T promoter allele in HCT116 cells), S4 (Transcriptional cooperation at the Flt1-T promoter between p53 and ERα ligand-activated ER), S5 (Half-site REs for p53 and ER+ligand are sufficient to yield synergistic transactivation at the Flt1-T promoter allele), and S6 (Estradiol treatment does not influence p53 levels in HCT116 cells)
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