Files in this Data Supplement:

• Supplemental file 1 - Fig. S1 (Phylogenetic analysis), S2 (Localization of MCJ and the endoplasmic reticulum), S3 (Doxorubicin intracellular accumulation in different cancer cell types), S4 (Determination of doxorubicin accumulation for MCB7/siMCJ-1B and -3B cells), S5 (Western blot analysis of ABCB1, c-Jun, and actin expression), S6 (HIF1α expression in MCB7 and siMCJ cells), and S7 (Emission spectral analysis)
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