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Signaling through ShcA Is Required for Transforming Growth Factor β- and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion
Mol. Cell. Biol. Northey et al. 28: 3162

Supplemental material

Files in this Data Supplement:

  • Supplemental file 1 - Fig. S1 (TGF-Β signaling and cytostatic responses in NMuMG explant cultures).
    Zipped PPT file, 6.5MB
  • Supplemental file 2 - Fig. S2 (TGF-Β-induced motility and invasion in Neu-NT-expressing mammary tumor explants cannot be explained by specific activation of RhoA or Rac1).
    Zipped PPT file,181K.
  • Supplemental file 3 - Fig. S3 (Establishment of NMuMG tumor explants expressing different Neu/ErbB-2 add-back mutants) .
    Zipped PPT file, 222K.
  • Supplemental file 4 - Fig. S4 (Mammary tumor explants expressing individual Neu/ErbB-2 add-back mutants undergo TGF-Β-induced signaling and remain sensitive to TGF-Β-mediated growth arrest).
    Zipped PPT file, 1.5MB.
  • Supplemental file 5 - Fig. S5 (Signaling through the ShcA adaptor protein is required for TGF-Β and Neu/ErbB-2 synergistic enhancement of breast cancer motility and invasion).
    Zipped PPT file, 1.6MB.
  • Supplemental file 6 - Fig. S6 (Immunofluorescence staining of explant populations for FAK and actin).
    Zipped PPT file, 4MB.
  • Supplemental file 7 - Fig. S7 (Immunofluorescence staining of explant populations for vinculin and actin).
    Zipped PPT file, 3.4MB
  • Supplemental file 8 - Legends to Fig. S1 to S7.
    MS Word document, 37K.




This Article
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