
Signaling through ShcA Is Required for Transforming Growth Factor β- and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion
Mol. Cell. Biol. Northey et al.
28: 3162
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
-
Fig. S1 (TGF-Β signaling and cytostatic responses in NMuMG explant cultures).
Zipped PPT file, 6.5MB
- Supplemental file 2
-
Fig. S2 (TGF-Β-induced motility and invasion in Neu-NT-expressing mammary tumor explants cannot be explained by specific activation of RhoA or Rac1).
Zipped PPT file,181K.
- Supplemental file 3
-
Fig. S3 (Establishment of NMuMG tumor explants expressing different Neu/ErbB-2 add-back mutants) .
Zipped PPT file, 222K.
- Supplemental file 4
-
Fig. S4 (Mammary tumor explants expressing individual Neu/ErbB-2 add-back mutants undergo TGF-Β-induced signaling and remain sensitive to TGF-Β-mediated growth arrest).
Zipped PPT file, 1.5MB.
- Supplemental file 5
-
Fig. S5 (Signaling through the ShcA adaptor protein is required for TGF-Β and Neu/ErbB-2 synergistic enhancement of breast cancer motility and invasion).
Zipped PPT file, 1.6MB.
- Supplemental file 6
-
Fig. S6 (Immunofluorescence staining of explant populations for FAK and actin).
Zipped PPT file, 4MB.
- Supplemental file 7
-
Fig. S7 (Immunofluorescence staining of explant populations for vinculin and actin).
Zipped PPT file, 3.4MB
- Supplemental file 8
-
Legends to Fig. S1 to S7.
MS Word document, 37K.