Supplemental material

Files in this Data Supplement:

• Supplemental file 1 - fig. S1 (PDK1 activity in different tissues of PDK1^K465E/K465E mice), S2 (Normal size of heterozygous PDK1^K465E/+ mice), S3 (Characterization of glucose homoeostasis in PDK1^K465E/K465E female mice), S4 (Blood glucose and plasma insulin levels in old PDK1^K465E/K465E mice), S5 (Quantitative analysis of PKB phosphorylation at Thr308 and Ser473 in PDK1^K465E/K465E muscle), S6 (Normal activation of RSK in PDK1^K465E/K465E ES cells and Immunoblotting of PKC isoforms in PDK1^K465E/K465E muscle), S7 (Muscle glucose transport in PDK1^K465E/K465E mice), and S8 (Expression of liver gluconeogenic and lipogenic genes in PDK1^K465E/K465E mice) .
  PDF document, 650K.
• Supplemental file 2 - Supplemental text, legends to Fig. S1 to S8, and Table S1 (Data for the PDK1[K465E] PH domain mutant).
  MS Word document, 155K.