Files in this Data Supplement:

• Supplemental file 1 - Fig. S1 (Identification of a silencing domain at the 5' end of Kcnq1ot1 RNA)
  EPS document, 620K.
• Supplemental file 2 - Fig. S2 (Characterization of Kcnq1ot1 silencing domain)
  EPS document, 619K.
• Supplemental file 3 - Fig. S3 (Real-time quantification of RNA PolII and TFIIB association to the overlapping H19 and nonoverlapping hygromycin promoters)
  EPS document, 1.1MB.
• Supplemental file 4 - Fig. S4 (Search for silencing domains in the 52-kb portion of more-than-90-kb Kcnq1ot1 transcript)
  EPS document, 434K.
• Supplemental file 5 - Fig. S5 (Effect of flanking chromatin-localizing region of Xist with the Kcnq1ot1 silencing domain on Kcnq1ot1 promoter activity and replacement of Kcnq1ot1 silencing domain with Xist silencing domain in PS6 episome has no effect on activity of Kcnq1ot1 promoter)
  EPS document, 431K.
• Supplemental file 6 - Fig. S6 (Kcnq1ot1 noncoding RNA colocalizes with episomal DNA)
  EPS document, 13.3MB.
• Supplemental file 7 - Supplemental figure legends
  Word document, 35K.