Files in this Data Supplement:

• Supplemental file 1 - Fig. S1 (Significant overlaps in AS events with a consistent change in exon inclusion levels), S2 (Effects of UPF factor knockdown on PTC-introducing AS events), S3 (Exon skipping predicted by AS microarray profiling and measured by RT-PCR assays), S4 (Overlapping but distinct effects of UPF factor knockdowns on PTC-introducing AS events), S5 (Frequency of changes in exon inclusion level upon knockdown of UPFs), and S6 to S8 (Cumulative distribution function plots of flanking intron sequence overlap with phastCons elements).
  PDF file, 1.4MB.
• Supplemental file 2 - Table S1 (Microarray data for 1,704 AS events).
  Zipped MS Excel file, 551K.
• Supplemental file 3 - Table S2 (Annotation for 1,704 microarray-monitored AS events).
  Zipped MS Excel file, 513K.
• Supplemental file 4 - Table S3 (Annotation for microarray-monitored AS events that introduce a PTC upon inclusion or skipping, have conserved flanking introns, and show changes in abundance upon UPF factor knockdown).
  Zipped MS Excel file,31K.
• Supplemental file 5 - Table S4 (Annotation of cassette AS events identified in spliceosome-associated genes).
  Zipped MS Excel file, 97K.
• Supplemental file 6 - Table S5 (Annotation of cassette AS events identified in the control gene set).
  Zipped MS Excel file, 104K.