A Novel Heme-Regulatory Motif Mediates Heme-Dependent Degradation of the Circadian Factor Period 2
Mol. Cell. Biol. Yang et al.
28: 4697
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Supplemental text and legends to Fig. S1 to S5.
MS Word file, 44K.
- Supplemental file 2
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Fig. S1 (Mdm2 levels are stable in the presence of heme).
Zipped TIF file, 208K.
- Supplemental file 3
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Fig. S2 (Heme binds to PAS-A subdomain of hPer2 with equimolar stoichiometry A).
Zipped TIF file, 208K.
- Supplemental file 4
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Fig. S3 (hCry1 levels are stable in the presence of heme).
Zipped TIF file, 660K.
- Supplemental file 5
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Fig. S4 (Tryptophan fluorescence studies of heme-hPer2 interaction).
Zipped TIF file, 65K.
- Supplemental file 6
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Fig. S5 (hPer2 stability in response to oxidative stress conditions).
Zipped TIF file, 506K.
