Files in this Data Supplement:

• Supplemental file 1 - List of DNA oligomers and Fig. S1 (Splicing is accurate), S2 (Connections between splicing and 3'-end processing), S3 (Cutting the tether prevents coupled 3'-end processing of the full-length ;beta-globin gene), S4 (Recalculation of Fig. 4B assuming selective loss of the unspliced precursors and repeat of Fig. 5 experiment with postcutting 147 nt upstream of the polyA site), and S5 (The uncleaved polyA signal enhances second-intron splicing)
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