β-Catenin Expression Results in p53-Independent DNA Damage and Oncogene-Induced Senescence in Prelymphomagenic Thymocytes In Vivo
Mol. Cell. Biol. Xu et al.
28: 1713
Supplemental material
Files in this Data Supplement:
- Supplemental file 2 -
Fig. S1 (Age-dependent decline in thymic cellularity in CAT-Tg mice), S2 (Up-regulation of cell cycle inhibitors, p15, and p16), S3 (Increased γH2AX staining in ex vivo CAT-Tg DN thymocytes), S4 (DN lymphomas in p53−/− CAT-Tg mice are c-kit− CD25− DN4-like thymocytes), and S5 (Thymocyte populations in lymphoma-bearing p53−/− CAT-Tg mice down-regulate p21 but not p15, p16, or p27)
PDF document, 846 KB.
- Supplemental file 1
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Legends to Fig. S1 to S5 and Tables S1 (Structural and numerical aberrations in chromosomes of p53−/− CAT-Tg lymphomas and p53+/+ CAT-Tg DN thymocytes) and S2 (Structural and numerical aberrations in chromosomes of lymphomas in p53−/− CAT-Tg mice)
Zipped MS Word document, 66 KB.
