
WRN Controls Formation of Extrachromosomal Telomeric Circles and Is Required for TRF2
B-Mediated Telomere Shortening
Mol. Cell. Biol. Li et al.
28: 1892
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Legends to Fig. S1 to S6
Zipped MS Word document, 9K.
- Supplemental file 2
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Fig. S1 (TRF2ΔB induction of TIFs)
Zipped EPS file, 2MB.
- Supplemental file 3
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Fig. S2 (Examples of the method used for quantification of telomeric signal)
Zipped EPS file, 4MB.
- Supplemental file 4
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Fig. S3 (Southern blot analysis of telomeric DNA in genetically complemented WS cells)
Zipped EPS file, 672KB.
- Supplemental file 5
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Fig. S4 (Quality control of blotted DNA and telomeric circles signal quantification)
Zipped EPS file, 6MB.
- Supplemental file 6
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Fig. S5 (Extrachromosomal double-stranded DNA circles are present in telomerase-positive WS fibroblasts)
Zipped EPS file, 10MB.
- Supplemental file 7
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Fig. S6 (Telomeric circles are present in telomerase-positive WS fibroblasts in the absence of TRF2ΔB)
Zipped EPS file, 2MB.