Files in this Data Supplement:

• Supplemental file 1 - Fig. S1 and S5 (qPCR validation of gene expression changes [S1] and Hnf1a ChIP assays [S5]), S2 (Glucose metabolism genes in Hnf1a^-/- islets), S3 and S4 (Frequency distribution [S3] and selective enrichment [S4] of conserved HNF1 motifs), S6 (IgG control ChIP-chip), S7 (Frequency of conserved HNF1 motifs and Hnf1α-dependent genes), S8 (T-antigen expression in Hnf1a^+/+ RipTAg and Hnf1a^-/- RipTAg β cells), and S9 (Hnf1β expression in Hnf1a^+/+ and Hnf1a^-/- cells); legends to Tables S1 to S6; and Table S5 (Hnf1α-dependent genes with roles in proliferation and tumorigenesis).
  PDF file, 1.1 MB.
• Supplemental file 2 - Tables S1 and S2 (Genes downregulated [S1] and upregulated [S2] in Hnf1a^-/- islets) and S3 and S4 (Genes downregulated [S3] and upregulated [S4] in Hnf1a^-/- liver).
  MS Excel file, 154K.
• Supplemental file 3 - Table S6 (Primers and Taqman assays used for RT- and ChIP-qPCR).
  MS Excel file, 29K.