Loss of the Tumor Suppressor Gene NF2, Encoding Merlin, Constitutively Activates Integrin-Dependent mTORC1 Signaling
Mol. Cell. Biol. López-Lago et al.
29: 4235
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Fig. S1 (DNA microarray analysis to determine transcriptomic and translation profiles).
Zipped EPS file, 1.7 MB.
- Supplemental file 2
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Fig. S2 (GST-Jun kinase assays of JNK activation and JNK depletion effect on phosphorylation of 4EBP1).
Zipped EPS file, 1.47 MB.
- Supplemental file 3
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Fig. S3 (Overexpression of merlin S518A and activation of S6K1).
Zipped EPS file, 1008K.
- Supplemental file 4
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Fig. S4 (Silencing of Merlin and downregulation of p27).
Zipped EPS file, 949K.
- Supplemental file 5
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Fig. S5 (siRNA depletion of Merlin rescues CAP-dependent translation on laminin 1).
Zipped EPS file, 886K.
- Supplemental file 6
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Fig. S6 (Depletion of Merlin and activation of S6K1, AKT, or ERK).
Zipped EPS file, 1.27 MB
