DNA Ligase I Deficiency Leads to Replication-Dependent DNA Damage and Impacts Cell Morphology without Blocking Cell Cycle Progression
Mol. Cell. Biol. Soza et al.
29: 2032
Supplemental material
Files in this Data Supplement:
- Supplemental file 6
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Supplemental text and legends to Fig. S1 to S5.
Zipped RTF file, 8K.
- Supplemental file 1
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Fig. S1 (DNA joining activity of epitope-tagged wild-type DNA ligase I and LigI-4D mutant expressed in 7A3 and M10 clones).
Zipped PDF file, 738K.
- Supplemental file 2
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Fig. S2 (Cell proliferation analysis).
Zipped PDF file, 73K.
- Supplemental file 3
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Fig. S3 (Comet assay analysis).
Zipped PDF file, 434K.
- Supplemental file 4
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Fig. S4 (DNA damage signaling in LigI-defective cells).
Zipped PDF file, 632K.
- Supplemental file 5
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Fig. S5 (Analysis of γH2AX foci in LigI-deficient cells).
Zipped PDF file, 297K.
