Files in this Data Supplement:

• Supplemental file 1 - Legends to Fig. S1 to S9.
  Zipped MS Word document, 7K.
• Supplemental file 2 - Fig. S1 (Downregulation of Nanog following LIF withdrawal).
  Zipped TIF file, 483K.
• Supplemental file 3 - Fig. S2 (Small-molecule inhibition of GSK3 activity and c-myc phosphorylation).
  Zipped TIF file, 110K.
• Supplemental file 4 - Fig. S3 (GSK3β accumulation following LIF withdrawal).
  Zipped TIF file, 891K.
• Supplemental file 5 - Fig. S4 (GSK3β localization in murine iPS cells and EpiSCs).
  Zipped TIF file, 1.3MB.
• Supplemental file 6 - Fig. S5 (AKTV inhibition of AKT1 effect on GSK3β accumulation).
  Zipped TIF file, 210K.
• Supplemental file 7 - Fig. S6 (PI-103 inhibition of PI3K effect on GSK3β accumulation).
  Zipped TIF file, 212K.
• Supplemental file 8 - Fig. S7 (PI3K inhibition effect on Nanog differentiation and c-myc phosphorylation).
  Zipped TIF file, 352K.
• Supplemental file 9 - Fig. S8 (GSK3β shuttling is independent of S9 phosphorylation).
  Zipped TIF file, 126K.
• Supplemental file 10 - Fig. S9 (T/brachyury and Cdx2 transcript levels).
  Zipped TIF file, 414K.