TABLE 1.
Survival frequency after induction of persistent HO breaks
| Strain | Genotype | Frequency of survival (fold reduction)a | Frequency of survivor type | |
|---|---|---|---|---|
| Ura+ | Ura− | |||
| SLY18 | Wild type | (1.22 ± 0.6) × 10−4 (1) | 4.33 × 10−5 | 7.87 × 10−5 |
| EMK10 | yku70Δ | (4.87 ± 2.7) × 10−6 (25) | 4.16 × 10−6 | 7.08 × 10−7 |
| SLY19 | Wild type | (6.00 ± 1.7) × 10−4 (1) | 9.60 × 10−5 | 5.04 × 10−4 |
| EMK11 | yku70Δ | (4.43 ± 1.6) × 10−4 (1.35) | 0 | 4.43 × 10−4 |
| EMK12 | rad52Δ | (7.57 ± 2.2) × 10−4 (0.79) | 5.25 × 10−5 | 7.05 × 10−4 |
| JLM30 | mre11Δ | (4.00 ± 2.4) × 10−5 (15) | 6.40 × 10−6 | 3.36 × 10−5 |
| JLM33 | rad50Δ | (1.33 ± 0.4) × 10−4 (4.5) | 0 | 1.33 × 10−4 |
| EMK13 | rad1Δ | (1.30 ± 0.3) × 10−4 (4.6) | 2.89 × 10−5 | 1.01 × 10−4 |
| JLM31 | rad1Δ yku70Δ | (9.93 ± 4.5) × 10−6 (60.4) | 6.45 × 10−6 | 3.48 × 10−6 |
| JLM32 | dnl4Δ | (1.34 ± 0.8) × 10−4 (4.47) | 1.09 × 10−5 | 1.23 × 10−4 |
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↵a Reduction was calculated by dividing the survival frequency of each mutant strain by that of either parental strain SLY18 or SLY19. Each value represents the average from at least three independent experiments ± standard deviation.
