Cover photograph (Copyright © 2001, American Society for Microbiology. All rights reserved.): Staining of bones and cartilage in the hind feet of 7-day-old Sox8-deficient mice by Alizarin red S and Alcian blue reveals a size reduction of several tarsals in the absence of Sox8 relative to wild-type mice. The original is shown, as are three variations in differently assigned colors. (See related article by Sock et al. in the next issue.)