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Contents: March 2001, Volume 21, Issue 5        Minireviews        Mammalian Genetic Models With Minimal Or Complex Phenotypes        Gene Expression        Cell Growth and Development        Transcriptional Regulation        Nucleocytoplasmic Communication        Dna Dynamics and Chromosome Structure        Errata

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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A Ras by Any Other Name Dafna Bar-Sagi Mol. Cell. Biol. March 2001 21: 1441-1443; [Full Text] [PDF] [Reprints and Permissions]

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Mammalian Genetic Models With Minimal Or Complex Phenotypes:

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Targeted Genomic Disruption of H-ras and N-ras, Individually or in Combination, Reveals the Dispensability of Both Loci for Mouse Growth and Development Luis M. Esteban, Carlos Vicario-Abejón, Pedro Fernández-Salguero, Alberto Fernández-Medarde, Nalini Swaminathan, Kate Yienger, Eva Lopez, Marcos Malumbres, Ron McKay, Jerrold M. Ward, Angel Pellicer, and Eugenio Santos Mol. Cell. Biol. March 2001 21: 1444-1452; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Craniofacial Dysmorphogenesis Including Cleft Palate in Mice with an Insertional Mutation in the discs large Gene Georgina Caruana and Alan Bernstein Mol. Cell. Biol. March 2001 21: 1475-1483; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Dach1 Mutant Mice Bear No Gross Abnormalities in Eye, Limb, and Brain Development and Exhibit Postnatal Lethality Richard J. Davis, Weiping Shen, Yakov I. Sandler, Mehran Amoui, Patricia Purcell, Richard Maas, Ching-Nan Ou, Hannes Vogel, Arthur L. Beaudet, and Graeme Mardon Mol. Cell. Biol. March 2001 21: 1484-1490; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

VAMP3 Null Mice Display Normal Constitutive, Insulin- and Exercise-Regulated Vesicle Trafficking Chunmei Yang, Silvia Mora, Jeffrey W. Ryder, Kenneth J. Coker, Polly Hansen, Lee-Ann Allen, and Jeffrey E. Pessin Mol. Cell. Biol. March 2001 21: 1573-1580; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Actinin-Associated LIM Protein-Deficient Mice Maintain Normal Development and Structure of Skeletal Muscle Kiwon Jo, Bart Rutten, Robert C. Bunn, and David S. Bredt Mol. Cell. Biol. March 2001 21: 1682-1687; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cardiomyopathy in Irx4-Deficient Mice Is Preceded by Abnormal Ventricular Gene Expression Benoit G. Bruneau, Zheng-Zheng Bao, Diane Fatkin, Jose Xavier-Neto, Dimitrios Georgakopoulos, Colin T. Maguire, Charles I. Berul, David A. Kass, Mercedes L. Kuroski-de Bold, Adolfo J. de Bold, David A. Conner, Nadia Rosenthal, Constance L. Cepko, Christine E. Seidman, and J. G. Seidman Mol. Cell. Biol. March 2001 21: 1730-1736; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Early Embryonic Lethality in PARP-1 Atm Double-Mutant Mice Suggests a Functional Synergy in Cell Proliferation during Development Josiane Ménissier-de Murcia, Manuel Mark, Olivia Wendling, Anthony Wynshaw-Boris, and Gilbert de Murcia Mol. Cell. Biol. March 2001 21: 1828-1832; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Gene Expression:

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The Saccharomyces cerevisiae TIF6 Gene Encoding Translation Initiation Factor 6 Is Required for 60S Ribosomal Subunit Biogenesis Uttiya Basu, Kausik Si, Jonathan R. Warner, and Umadas Maitra Mol. Cell. Biol. March 2001 21: 1453-1462; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Insight into Mammalian Selenocysteine Insertion: Domain Structure and Ribosome Binding Properties of Sec Insertion Sequence Binding Protein 2 Paul R. Copeland, Vincent A. Stepanik, and Donna M. Driscoll Mol. Cell. Biol. March 2001 21: 1491-1498; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

An Upstream AG Determines Whether a Downstream AG Is Selected during Catalytic Step II of Splicing Katrin Chua and Robin Reed Mol. Cell. Biol. March 2001 21: 1509-1514; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Upf1p, Nmd2p, and Upf3p Regulate the Decapping and Exonucleolytic Degradation of both Nonsense-Containing mRNAs and Wild-Type mRNAs Feng He and Allan Jacobson Mol. Cell. Biol. March 2001 21: 1515-1530; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Zygotic Regulation of Maternal Cyclin A1 and B2 mRNAs Yann Audic, Christina Anderson, Robert Bhatty, and Rebecca S. Hartley Mol. Cell. Biol. March 2001 21: 1662-1671; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Ambient pH Signaling Regulates Nuclear Localization of the Aspergillus nidulans PacC Transcription Factor José M. Mingot, Eduardo A. Espeso, Eliecer Díez, and Miguel Á. Peñalva Mol. Cell. Biol. March 2001 21: 1688-1699; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

c-myc Internal Ribosome Entry Site Activity Is Developmentally Controlled and Subjected to a Strong Translational Repression in Adult Transgenic Mice Laurent Créancier, Pascale Mercier, Anne-Catherine Prats, and Dominique Morello Mol. Cell. Biol. March 2001 21: 1833-1840; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

HIRA, the Human Homologue of Yeast Hir1p and Hir2p, Is a Novel Cyclin-cdk2 Substrate Whose Expression Blocks S-Phase Progression Caitlin Hall, David M. Nelson, Xiaofen Ye, Kayla Baker, James A. DeCaprio, Steven Seeholzer, Marc Lipinski, and Peter D. Adams Mol. Cell. Biol. March 2001 21: 1854-1865; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Cell Growth and Development:

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Autoinhibition Mechanism of Proto-Dbl Feng Bi, Balazs Debreceni, Kejin Zhu, Barbara Salani, Alessandra Eva, and Yi Zheng Mol. Cell. Biol. March 2001 21: 1463-1474; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Roles of the Mitotic Inhibitors Wee1 and Mik1 in the G2 DNA Damage and Replication Checkpoints Nicholas Rhind and Paul Russell Mol. Cell. Biol. March 2001 21: 1499-1508; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Grb2 and Shc Adapter Proteins Play Distinct Roles in Neu (ErbB-2)-Induced Mammary Tumorigenesis: Implications for Human Breast Cancer David Dankort, Bart Maslikowski, Neil Warner, Nubufumi Kanno, Harold Kim, Zhixiang Wang, Michael F. Moran, Robert G. Oshima, Robert D. Cardiff, and William J. Muller Mol. Cell. Biol. March 2001 21: 1540-1551; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Change of the Death Pathway in Senescent Human Fibroblasts in Response to DNA Damage Is Caused by an Inability To Stabilize p53 Andrei Seluanov, Vera Gorbunova, Ayellet Falcovitz, Alex Sigal, Michael Milyavsky, Irit Zurer, Galit Shohat, Naomi Goldfinger, and Varda Rotter Mol. Cell. Biol. March 2001 21: 1552-1564; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Selective Expression of an Endogenous Inhibitor of FAK Regulates Proliferation and Migration of Vascular Smooth Muscle Cells Joan M. Taylor, Christopher P. Mack, Kate Nolan, Christopher P. Regan, Gary K. Owens, and J. Thomas Parsons Mol. Cell. Biol. March 2001 21: 1565-1572; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Positive Regulator of Mitosis, Sok2, Functions as a Negative Regulator of Meiosis in Saccharomyces cerevisiae Galit Shenhar and Yona Kassir Mol. Cell. Biol. March 2001 21: 1603-1612; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

SH2-B and APS Are Multimeric Adapters That Augment TrkA Signaling Xiaozhong Qian and David D. Ginty Mol. Cell. Biol. March 2001 21: 1613-1620; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Essential Role of STAT3 in the Control of the Acute-Phase Response as Revealed by Inducible Gene Activation in the Liver Tonino Alonzi, Diego Maritano, Barbara Gorgoni, Gabriella Rizzuto, Claude Libert, and Valeria Poli Mol. Cell. Biol. March 2001 21: 1621-1632; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Overexpression of SH2-Containing Inositol Phosphatase 2 Results in Negative Regulation of Insulin-Induced Metabolic Actions in 3T3-L1 Adipocytes via Its 5'-Phosphatase Catalytic Activity Tsutomu Wada, Toshiyasu Sasaoka, Makoto Funaki, Hiroyuki Hori, Shihou Murakami, Manabu Ishiki, Tetsuro Haruta, Tomoichiro Asano, Wataru Ogawa, Hajime Ishihara, and Masashi Kobayashi Mol. Cell. Biol. March 2001 21: 1633-1646; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Subtype-Specific Translocation of the Subtype of Protein Kinase C and Its Activation by Tyrosine Phosphorylation Induced by Ceramide in HeLa Cells Taketoshi Kajimoto, Shiho Ohmori, Yasuhito Shirai, Norio Sakai, and Naoaki Saito Mol. Cell. Biol. March 2001 21: 1769-1783; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Protein Tyrosine Phosphatase Regulates Paxillin Tyrosine Phosphorylation and Mediates Colony-Stimulating Factor 1-Induced Morphological Changes in Macrophages Fiona J. Pixley, Pierre S. W. Lee, John S. Condeelis, and E. Richard Stanley Mol. Cell. Biol. March 2001 21: 1795-1809; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibition of Tcf3 Binding by I-mfa Domain Proteins Lauren Snider, Hilary Thirlwell, Jeffrey R. Miller, Randall T. Moon, Mark Groudine, and Stephen J. Tapscott Mol. Cell. Biol. March 2001 21: 1866-1873; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain C. Gaiddon, M. Lokshin, J. Ahn, T. Zhang, and C. Prives Mol. Cell. Biol. March 2001 21: 1874-1887; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Transcriptional Regulation:

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The B Lymphocyte-Specific Coactivator BOB.1/OBF.1 Is Required at Multiple Stages of B-Cell Development Jochen Hess, Peter J. Nielsen, Klaus-Dieter Fischer, Hermann Bujard, and Thomas Wirth Mol. Cell. Biol. March 2001 21: 1531-1539; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interpretation of X Chromosome Dose at Sex-lethal Requires Non-E-Box Sites for the Basic Helix-Loop-Helix Proteins SISB and Daughterless Dun Yang, Hong Lu, Yong Hong, Timothy M. Jinks, Patricia A. Estes, and James W. Erickson Mol. Cell. Biol. March 2001 21: 1581-1592; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Analysis of Core Promoter Sequences Located Downstream from the TATA Element in the hsp70 Promoter from Drosophila melanogaster Chwen-Huey Wu, Lakshmi Madabusi, Hokuto Nishioka, Peter Emanuel, Michael Sypes, Irina Arkhipova, and David S. Gilmour Mol. Cell. Biol. March 2001 21: 1593-1602; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Analysis of the Leukemia Protein ELL: Evidence for a Role in the Regulation of Cell Growth and Survival Ricky W. Johnstone, Mark Gerber, Theresa Landewe, Anne Tollefson, William S. Wold, and Ali Shilatifard Mol. Cell. Biol. March 2001 21: 1672-1681; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

TFIIA Interacts with TFIID via Association with TATA-Binding Protein and TAF40 Susan M. Kraemer, Ryan T. Ranallo, Ryan C. Ogg, and Laurie A. Stargell Mol. Cell. Biol. March 2001 21: 1737-1746; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Determinants of CoRNR-Dependent Repression Complex Assembly on Nuclear Hormone Receptors Xiao Hu, Yun Li, and Mitchell A. Lazar Mol. Cell. Biol. March 2001 21: 1747-1758; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Balance of Nuclear Import and Export Determines the Intracellular Distribution and Function of Tomato Heat Stress Transcription Factor HsfA2 Dirk Heerklotz, Pascal Döring, Frank Bonzelius, Sybille Winkelhaus, and Lutz Nover Mol. Cell. Biol. March 2001 21: 1759-1768; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Histone Folds Mediate Selective Heterodimerization of Yeast TAFII25 with TFIID Components yTAFII47 and yTAFII65 and with SAGA Component ySPT7 Yann-Gaël Gangloff, Steven L. Sanders, Christophe Romier, Doris Kirschner, P. Anthony Weil, Laszlo Tora, and Irwin Davidson Mol. Cell. Biol. March 2001 21: 1841-1853; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Nucleocytoplasmic Communication:

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Pir1p Mediates Translocation of the Yeast Apn1p Endonuclease into the Mitochondria To Maintain Genomic Stability Ratsavarinh Vongsamphanh, Pierre-Karl Fortier, and Dindial Ramotar Mol. Cell. Biol. March 2001 21: 1647-1655; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Proteasome Inhibition Induces Nuclear Translocation and Transcriptional Activation of the Dioxin Receptor in Mouse Embryo Primary Fibroblasts in the Absence of Xenobiotics Belen Santiago-Josefat, Eulalia Pozo-Guisado, Sonia Mulero-Navarro, and Pedro M. Fernandez-Salguero Mol. Cell. Biol. March 2001 21: 1700-1709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

CAC3 (MSI1) Suppression of RAS2G19V Is Independent of Chromatin Assembly Factor I and Mediated by NPR1 Stephen D. Johnston, Shinichiro Enomoto, Lisa Schneper, Mark C. McClellan, Florence Twu, Nathan D. Montgomery, Steven A. Haney, James R. Broach, and Judith Berman Mol. Cell. Biol. March 2001 21: 1784-1794; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Dna Dynamics and Chromosome Structure:

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3'-Phosphodiesterase and 3'5' Exonuclease Activities of Yeast Apn2 Protein and Requirement of These Activities for Repair of Oxidative DNA Damage Ildiko Unk, Lajos Haracska, Satya Prakash, and Louise Prakash Mol. Cell. Biol. March 2001 21: 1656-1661; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Checkpoint Adaptation Precedes Spontaneous and Damage-Induced Genomic Instability in Yeast David J. Galgoczy and David P. Toczyski Mol. Cell. Biol. March 2001 21: 1710-1718; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phosphorylation and Rapid Relocalization of 53BP1 to Nuclear Foci upon DNA Damage Lindsay Anderson, Catherine Henderson, and Yasuhisa Adachi Mol. Cell. Biol. March 2001 21: 1719-1729; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Disruption of the Cockayne Syndrome B Gene Impairs Spontaneous Tumorigenesis in Cancer-Predisposed Ink4a/ARF Knockout Mice Yi Lu, Hanzhou Lian, Prerna Sharma, Nicole Schreiber-Agus, Robert G. Russell, Lynda Chin, Gijsbertus T. J. van der Horst, and David B. Bregman Mol. Cell. Biol. March 2001 21: 1810-1818; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Two Survivor Pathways That Allow Growth in the Absence of Telomerase Are Generated by Distinct Telomere Recombination Events Qijun Chen, Arne Ijpma, and Carol W. Greider Mol. Cell. Biol. March 2001 21: 1819-1827; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Regions of Human Telomerase Reverse Transcriptase and Human Telomerase RNA Required for Telomerase Activity and RNA-Protein Interactions François Bachand and Chantal Autexier Mol. Cell. Biol. March 2001 21: 1888-1897; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Errata:

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DNA Damage-Dependent Nuclear Dynamics of the Mre11 Complex Olga K. Mirzoeva and John H. J. Petrini Mol. Cell. Biol. March 2001 21: 1898 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.