Cover photograph (Copyright © 2002, American Society for Microbiology. All Rights Reserved.): A chimeric protein containing the Insc minimal functional domain and the Pins C-terminal region possesses both insc and pins function. Double label of Insc/Pins chimeric protein (green) and endogenous Insc (red) in Pins^- neuroblasts indicates that the chimeric protein is unable to recruit Insc to the apical cortex (superimposed image). (See related article on p. 4230.)