Cover photograph (Copyright © 2002, American Society for Microbiology. All Rights Reserved.): Translocation of the carboxy-terminal hRad21 cohesin protein to the cytoplasm following induction of apoptosis in mammary epithelial cells. Induction of apoptosis results in the generation of 60- and 64-kDa carboxy-terminal hRad21 cleavage products. hRad21 is a nuclear protein; however, the cleaved 64-kDa carboxy-terminal product is translocated to the cytoplasm early in apoptosis before chromatin condensation and nuclear fragmentation. (See related article on p. 8267.)