Cover photograph (Copyright © 2003, American Society for Microbiology. All Rights Reserved.): Confocal image of COS-7 cells showing RhoE localization. The cells were stained with polyclonal (green) and monoclonal (red) anti-RhoE antibodies, and regions of overlap are shown in yellow. Filamentous actin was stained with labeled phalloidin and is shown in blue to indicate cell shape. (See related article in June 2003, issue 12: vol. 23, p.4219.)