About This Cover Other Issues

Contents: August 2004, Volume 24, Issue 15        Mammalian Genetic Models With Minimal Or Complex Phenotypes        Transcriptional Regulation        Cell Growth and Development        Nucleocytoplasmic Communication        Dna Dynamics and Chromosome Structure        Gene Expression        Errata        Author's Correction

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

---

Mammalian Genetic Models With Minimal Or Complex Phenotypes:

---

Mnk2 and Mnk1 Are Essential for Constitutive and Inducible Phosphorylation of Eukaryotic Initiation Factor 4E but Not for Cell Growth or Development Takeshi Ueda, Rie Watanabe-Fukunaga, Hidehiro Fukuyama, Shigekazu Nagata, and Rikiro Fukunaga Mol. Cell. Biol. August 2004 24: 6539-6549; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Telomere-Associated Protein TIN2 Is Essential for Early Embryonic Development through a Telomerase-Independent Pathway Y. Jeffrey Chiang, Sahn-Ho Kim, Lino Tessarollo, Judith Campisi, and Richard J. Hodes Mol. Cell. Biol. August 2004 24: 6631-6634; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Gene Targeting Reveals a Widespread Role for the High-Mobility-Group Transcription Factor Sox11 in Tissue Remodeling Elisabeth Sock, Stefanie D. Rettig, Janna Enderich, Michael R. Bösl, Ernst R. Tamm, and Michael Wegner Mol. Cell. Biol. August 2004 24: 6635-6644; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells Mirei Murakami, Tomoko Ichisaka, Mitsuyo Maeda, Noriko Oshiro, Kenta Hara, Frank Edenhofer, Hiroshi Kiyama, Kazuyoshi Yonezawa, and Shinya Yamanaka Mol. Cell. Biol. August 2004 24: 6710-6718; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Gene-Targeted Mice Lacking the Trex1 (DNase III) 3'5' DNA Exonuclease Develop Inflammatory Myocarditis Masashi Morita, Gordon Stamp, Peter Robins, Anna Dulic, Ian Rosewell, Geza Hrivnak, Graham Daly, Tomas Lindahl, and Deborah E. Barnes Mol. Cell. Biol. August 2004 24: 6719-6727; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Transcriptional Regulation:

---

The Microphthalmia Transcription Factor (Mitf) Controls Expression of the Ocular Albinism Type 1 Gene: Link between Melanin Synthesis and Melanosome Biogenesis Francesco Vetrini, Alberto Auricchio, Jinyan Du, Barbara Angeletti, David E. Fisher, Andrea Ballabio, and Valeria Marigo Mol. Cell. Biol. August 2004 24: 6550-6559; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cross Talk between Retinoic Acid Signaling and Transcription Factor GATA-2 Shinobu Tsuzuki, Kenji Kitajima, Toru Nakano, Annegret Glasow, Arthur Zelent, and Tariq Enver Mol. Cell. Biol. August 2004 24: 6824-6836; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Triad of Subunits from the Gal11/Tail Domain of Srb Mediator Is an In Vivo Target of Transcriptional Activator Gcn4p Fan Zhang, Laarni Sumibcay, Alan G. Hinnebusch, and Mark J. Swanson Mol. Cell. Biol. August 2004 24: 6871-6886; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Cell Growth and Development:

---

Bone Morphogenetic Protein 2-Induced Osteoblast Differentiation Requires Smad-Mediated Down-Regulation of Cdk6 Toru Ogasawara, Hiroshi Kawaguchi, Shigeki Jinno, Kazuto Hoshi, Keiji Itaka, Tsuyoshi Takato, Kozo Nakamura, and Hiroto Okayama Mol. Cell. Biol. August 2004 24: 6560-6568; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Menin Missense Mutants Associated with Multiple Endocrine Neoplasia Type 1 Are Rapidly Degraded via the Ubiquitin-Proteasome Pathway Hiroko Yaguchi, Naganari Ohkura, Maho Takahashi, Yuko Nagamura, Issay Kitabayashi, and Toshihiko Tsukada Mol. Cell. Biol. August 2004 24: 6569-6580; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Metastasis-Associated Protein 1 Interacts with NRIF3, an Estrogen-Inducible Nuclear Receptor Coregulator Amjad H. Talukder, Anupama Gururaj, Sandip K. Mishra, Ratna K. Vadlamudi, and Rakesh Kumar Mol. Cell. Biol. August 2004 24: 6581-6591; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Association of Active Caspase 8 with the Mitochondrial Membrane during Apoptosis: Potential Roles in Cleaving BAP31 and Caspase 3 and Mediating Mitochondrion-Endoplasmic Reticulum Cross Talk in Etoposide-Induced Cell Death Dhyan Chandra, Grace Choy, Xiaodi Deng, Bobby Bhatia, Peter Daniel, and Dean G. Tang Mol. Cell. Biol. August 2004 24: 6592-6607; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Vitamin C Is a Kinase Inhibitor: Dehydroascorbic Acid Inhibits IB Kinase ß Juan M. Cárcamo, Alicia Pedraza, Oriana Bórquez-Ojeda, Bing Zhang, Roberto Sanchez, and David W. Golde Mol. Cell. Biol. August 2004 24: 6645-6652; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Evidence for Functional Dependency of p18Ink4c on Cdk4 Xin-Hai Pei, Feng Bai, Tateki Tsutsui, Hiroaki Kiyokawa, and Yue Xiong Mol. Cell. Biol. August 2004 24: 6653-6664; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nucleotide Exchange Factor ECT2 Interacts with the Polarity Protein Complex Par6/Par3/Protein Kinase C (PKC) and Regulates PKC Activity Xiu-Fen Liu, Hiroshi Ishida, Razi Raziuddin, and Toru Miki Mol. Cell. Biol. August 2004 24: 6665-6675; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Drosophila C-Terminal Src Kinase Negatively Regulates Organ Growth and Cell Proliferation through Inhibition of the Src, Jun N-Terminal Kinase, and STAT Pathways Renee D. Read, Erika A. Bach, and Ross L. Cagan Mol. Cell. Biol. August 2004 24: 6676-6689; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rap1 Regulates the Formation of E-Cadherin-Based Cell-Cell Contacts Catherine Hogan, Norberto Serpente, Patricia Cogram, Catherine Rose Hosking, Carl Uli Bialucha, Stephan Michael Feller, Vania M. M. Braga, Walter Birchmeier, and Yasuyuki Fujita Mol. Cell. Biol. August 2004 24: 6690-6700; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vivo Mitochondrial p53 Translocation Triggers a Rapid First Wave of Cell Death in Response to DNA Damage That Can Precede p53 Target Gene Activation Susan Erster, Motohiro Mihara, Roger H. Kim, Oleksi Petrenko, and Ute M. Moll Mol. Cell. Biol. August 2004 24: 6728-6741; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Dissection of a Natural RNA Silencing Process in the Drosophila melanogaster Germ Line Alexei A. Aravin, Mikhail S. Klenov, Vasilii V. Vagin, Frédéric Bantignies, Giacomo Cavalli, and Vladimir A. Gvozdev Mol. Cell. Biol. August 2004 24: 6742-6750; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reactive Nitrogen Species-Induced Cell Death Requires Fas-Dependent Activation of c-Jun N-Terminal Kinase Punya Shrivastava, Cristen Pantano, Richard Watkin, Brian McElhinney, Amy Guala, Matthew L. Poynter, Rebecca L. Persinger, Ralph Budd, and Yvonne Janssen-Heininger Mol. Cell. Biol. August 2004 24: 6763-6772; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

RACK1 Regulates G1/S Progression by Suppressing Src Kinase Activity Vidya Mamidipudi, Jian Zhang, Kelly C. Lee, and Christine A. Cartwright Mol. Cell. Biol. August 2004 24: 6788-6798; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane Barak Rotblat, Ian A. Prior, Cornelia Muncke, Robert G. Parton, Yoel Kloog, Yoav I. Henis, and John F. Hancock Mol. Cell. Biol. August 2004 24: 6799-6810; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Gene Expression Analysis of Tumor Spheroids Reveals a Role for Suppressed DNA Mismatch Repair in Multicellular Resistance to Alkylating Agents Giulio Francia, Shan Man, Beverly Teicher, Luigi Grasso, and Robert S. Kerbel Mol. Cell. Biol. August 2004 24: 6837-6849; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Nucleocytoplasmic Communication:

---

Nucleocytoplasmic Shuttling of JAZ, a New Cargo Protein for Exportin-5 Ting Chen, Amy M. Brownawell, and Ian G. Macara Mol. Cell. Biol. August 2004 24: 6608-6619; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Thrombopoietin Induces HOXA9 Nuclear Transport in Immature Hematopoietic Cells: Potential Mechanism by Which the Hormone Favorably Affects Hematopoietic Stem Cells Keita Kirito, Norma Fox, and Kenneth Kaushansky Mol. Cell. Biol. August 2004 24: 6751-6762; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Dna Dynamics and Chromosome Structure:

---

Functional Complementation of Human Centromere Protein A (CENP-A) by Cse4p from Saccharomyces cerevisiae Gerhard Wieland, Sandra Orthaus, Sabine Ohndorf, Stephan Diekmann, and Peter Hemmerich Mol. Cell. Biol. August 2004 24: 6620-6630; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

BRCA1 Is Required for Common-Fragile-Site Stability via Its G2/M Checkpoint Function Martin F. Arlt, Bo Xu, Sandra G. Durkin, Anne M. Casper, Michael B. Kastan, and Thomas W. Glover Mol. Cell. Biol. August 2004 24: 6701-6709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

DNA Cleavage Activity of the V(D)J Recombination Protein RAG1 Is Autoregulated Pallabi De, Mandy M. Peak, and Karla K. Rodgers Mol. Cell. Biol. August 2004 24: 6850-6860; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Gene Expression:

---

Global mRNA Stabilization Preferentially Linked to Translational Repression during the Endoplasmic Reticulum Stress Response Tomoko Kawai, Jinshui Fan, Krystyna Mazan-Mamczarz, and Myriam Gorospe Mol. Cell. Biol. August 2004 24: 6773-6787; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

SMU-2 and SMU-1, Caenorhabditis elegans Homologs of Mammalian Spliceosome-Associated Proteins RED and fSAP57, Work Together To Affect Splice Site Choice Angela K. Spartz, Robert K. Herman, and Jocelyn E. Shaw Mol. Cell. Biol. August 2004 24: 6811-6823; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

La Autoantigen Is Necessary for Optimal Function of the Poliovirus and Hepatitis C Virus Internal Ribosome Entry Site In Vivo and In Vitro Mauro Costa-Mattioli, Yuri Svitkin, and Nahum Sonenberg Mol. Cell. Biol. August 2004 24: 6861-6870; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

---

Errata:

---

Fibroblast Growth Factor 2-Mediated Translational Control of IAPs Blocks Mitochondrial Release of Smac/DIABLO and Apoptosis in Small Cell Lung Cancer Cells Olivier E. Pardo, Adeline Lesay, Alexandre Arcaro, Rita Lopes, Bee Ling Ng, Patricia H. Warne, Iain A. McNeish, Teresa D. Tetley, Nicholas R. Lemoine, Huseyin Mehmet, Michael J. Seckl, and Julian Downward Mol. Cell. Biol. August 2004 24: 6887 [Full Text] [PDF] [Reprints and Permissions]

---

Author's Correction:

---

HuD RNA Recognition Motifs Play Distinct Roles in the Formation of a Stable Complex with AU-Rich RNA Sungmin Park, David G. Myszka, Michael Yu, Sarah J. Littler, and Ite A. Laird-Offringa Mol. Cell. Biol. August 2004 24: 6888 [Full Text] [PDF] [Reprints and Permissions]

Polypyrimidine Tract Binding Protein Modulates Efficiency of Polyadenylation Pedro Castelo-Branco, Andre Furger, Matthew Wollerton, Christopher Smith, Alexandra Moreira, and Nick Proudfoot Mol. Cell. Biol. August 2004 24: 6889 [Full Text] [PDF] [Reprints and Permissions]

Potentiation of Tumor Necrosis Factor-Induced NF-B Activation by Deacetylase Inhibitors Is Associated with a Delayed Cytoplasmic Reappearance of IB Emmanuelle Adam, Vincent Quivy, Françoise Bex, Alain Chariot, Yves Collette, Caroline Vanhulle, Sonia Schoonbroodt, Véronique Goffin, Thi Liên-Anh Nguyên, Geoffrey Gloire, Géraldine Carrard, Bertrand Friguet, Yvan de Launoit, Arsène Burny, Vincent Bours, Jacques Piette, and Carine Van Lint Mol. Cell. Biol. August 2004 24: 6890 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.