Cover photograph (Copyright © 2004, American Society for Microbiology. All Rights Reserved.): An active form of the cytoplasmic protein tyrosine kinase c-Fes shows strong localization to the tubulin cytoskeleton in confocal images of transfected COS-7 cells. Cells were stained with phosphospecific antibodies against Fes (blue) and alpha-tubulin antibodies (red). The Fes protein is tagged with green fluorescent protein (green). A merged imaged is shown at the lower right; colocalizing images appear as white areas. (See related article on p. 9351.)