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Contents: November 2004, Volume 24, Issue 21        Cell Growth and Development        Dna Dynamics and Chromosome Structure        Gene Expression        Transcriptional Regulation        Mammalian Genetic Models With Minimal Or Complex Phenotypes

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Cell Growth and Development:

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Notch Subunit Heterodimerization and Prevention of Ligand-Independent Proteolytic Activation Depend, Respectively, on a Novel Domain and the LNR Repeats Cheryll Sanchez-Irizarry, Andrea C. Carpenter, Andrew P. Weng, Warren S. Pear, Jon C. Aster, and Stephen C. Blacklow Mol. Cell. Biol. November 2004 24: 9265-9273; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

FF Domains of CA150 Bind Transcription and Splicing Factors through Multiple Weak Interactions Matthew J. Smith, Sarang Kulkarni, and Tony Pawson Mol. Cell. Biol. November 2004 24: 9274-9285; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Immunodeficiency Virus Type 1 Vpr-Mediated G2 Arrest Requires Rad17 and Hus1 and Induces Nuclear BRCA1 and -H2AX Focus Formation Erik S. Zimmerman, Junjie Chen, Joshua L. Andersen, Orly Ardon, Jason L. DeHart, Jana Blackett, Shailesh K. Choudhary, David Camerini, Paul Nghiem, and Vicente Planelles Mol. Cell. Biol. November 2004 24: 9286-9294; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Conditional Activation of Akt in Adult Skeletal Muscle Induces Rapid Hypertrophy Ka-Man V. Lai, Michael Gonzalez, William T. Poueymirou, William O. Kline, Erqian Na, Elizabeth Zlotchenko, Trevor N. Stitt, Aris N. Economides, George D. Yancopoulos, and David J. Glass Mol. Cell. Biol. November 2004 24: 9295-9304; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ARF Impedes NPM/B23 Shuttling in an Mdm2-Sensitive Tumor Suppressor Pathway Suzanne N. Brady, Yue Yu, Leonard B. Maggi, Jr., and Jason D. Weber Mol. Cell. Biol. November 2004 24: 9327-9338; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

BRUCE, a Giant E2/E3 Ubiquitin Ligase and Inhibitor of Apoptosis Protein of the trans-Golgi Network, Is Required for Normal Placenta Development and Mouse Survival Kristina Lotz, George Pyrowolakis, and Stefan Jentsch Mol. Cell. Biol. November 2004 24: 9339-9350; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Human c-Fes Tyrosine Kinase Binds Tubulin and Microtubules through Separate Domains and Promotes Microtubule Assembly Charles E. Laurent, Frank J. Delfino, Haiyun Y. Cheng, and Thomas E. Smithgall Mol. Cell. Biol. November 2004 24: 9351-9358; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ALK7, a Receptor for Nodal, Is Dispensable for Embryogenesis and Left-Right Patterning in the Mouse Henrik Jörnvall, Eva Reissmann, Olov Andersson, Mehrnaz Mehrkash, and Carlos F. Ibáñez Mol. Cell. Biol. November 2004 24: 9383-9389; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Central Role of the Threonine Residue within the p+1 Loop of Receptor Tyrosine Kinase in STAT3 Constitutive Phosphorylation in Metastatic Cancer Cells Zheng-long Yuan, Ying-jie Guan, Lijuan Wang, Wenyi Wei, Agnes B. Kane, and Y. Eugene Chin Mol. Cell. Biol. November 2004 24: 9390-9400; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Essential Role for Mitochondrial Thioredoxin Reductase in Hematopoiesis, Heart Development, and Heart Function Marcus Conrad, Cemile Jakupoglu, Stéphanie G. Moreno, Stefanie Lippl, Ana Banjac, Manuela Schneider, Heike Beck, Antonis K. Hatzopoulos, Ursula Just, Fred Sinowatz, Wolfgang Schmahl, Kenneth R. Chien, Wolfgang Wurst, Georg W. Bornkamm, and Markus Brielmeier Mol. Cell. Biol. November 2004 24: 9414-9423; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of Stanniocalcin 2, a Novel Target of the Mammalian Unfolded Protein Response with Cytoprotective Properties Daisuke Ito, John R. Walker, Charlie S. Thompson, Isabella Moroz, William Lin, Margaret L. Veselits, Antoine M. Hakim, Allen A. Fienberg, and Gopal Thinakaran Mol. Cell. Biol. November 2004 24: 9456-9469; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of the Proteins Required for Biosynthesis of Diphthamide, the Target of Bacterial ADP-Ribosylating Toxins on Translation Elongation Factor 2 Shihui Liu, G. Todd Milne, Jeffrey G. Kuremsky, Gerald R. Fink, and Stephen H. Leppla Mol. Cell. Biol. November 2004 24: 9487-9497; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Uterus Hyperplasia and Increased Carcinogen-Induced Tumorigenesis in Mice Carrying a Targeted Mutation of the Chk2 Phosphorylation Site in Brca1 Sang Soo Kim, Liu Cao, Cuiling Li, Xiaoling Xu, L. Julie Huber, Lewis A. Chodosh, and Chu-Xia Deng Mol. Cell. Biol. November 2004 24: 9498-9507; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Disruption of the Rb-Raf-1 Interaction Inhibits Tumor Growth and Angiogenesis Piyali Dasgupta, Jiazhi Sun, Sheng Wang, Gina Fusaro, Vicki Betts, Jaya Padmanabhan, Saïd M. Sebti, and Srikumar P. Chellappan Mol. Cell. Biol. November 2004 24: 9527-9541; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interferon-Inducible Ubiquitin E2, Ubc8, Is a Conjugating Enzyme for Protein ISGylation Keun Il Kim, Nadia V. Giannakopoulos, Herbert W. Virgin, and Dong-Er Zhang Mol. Cell. Biol. November 2004 24: 9592-9600; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lipopolysaccharide Activation of the TPL-2/MEK/Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Cascade Is Regulated by IB Kinase-Induced Proteolysis of NF-B1 p105 S. Beinke, M. J. Robinson, M. Hugunin, and S. C. Ley Mol. Cell. Biol. November 2004 24: 9658-9667; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Serine Phosphorylation Proximal to Its Phosphotyrosine Binding Domain Inhibits Insulin Receptor Substrate 1 Function and Promotes Insulin Resistance Yan-Fang Liu, Avia Herschkovitz, Sigalit Boura-Halfon, Denise Ronen, Keren Paz, Derek LeRoith, and Yehiel Zick Mol. Cell. Biol. November 2004 24: 9668-9681; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Dna Dynamics and Chromosome Structure:

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Genetic Steps of Mammalian Homologous Repair with Distinct Mutagenic Consequences Jeremy M. Stark, Andrew J. Pierce, Jin Oh, Albert Pastink, and Maria Jasin Mol. Cell. Biol. November 2004 24: 9305-9316; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Generic Features of Tertiary Chromatin Structure as Detected in Natural Chromosomes Waltraud G. Müller, Dietmar Rieder, Gregor Kreth, Christoph Cremer, Zlatko Trajanoski, and James G. McNally Mol. Cell. Biol. November 2004 24: 9359-9370; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rad62 Protein Functionally and Physically Associates with the Smc5/Smc6 Protein Complex and Is Required for Chromosome Integrity and Recombination Repair in Fission Yeast Hirofumi Morikawa, Takashi Morishita, Shiho Kawane, Hiroshi Iwasaki, Antony M. Carr, and Hideo Shinagawa Mol. Cell. Biol. November 2004 24: 9401-9413; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

DNA Damage-Induced Cell Cycle Checkpoint Control Requires CtIP, a Phosphorylation-Dependent Binding Partner of BRCA1 C-Terminal Domains Xiaochun Yu and Junjie Chen Mol. Cell. Biol. November 2004 24: 9478-9486; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Fission Yeast Dna2 Is Required for Generation of the Telomeric Single-Strand Overhang Kazunori Tomita, Tatsuya Kibe, Ho-Young Kang, Yeon-Soo Seo, Masahiro Uritani, Takashi Ushimaru, and Masaru Ueno Mol. Cell. Biol. November 2004 24: 9557-9567; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Coordinated Temporal Interplay of Nucleosome Reorganization Factor, Sister Chromatin Cohesion Factor, and DNA Polymerase Facilitates DNA Replication Yanjiao Zhou and Teresa S.-F. Wang Mol. Cell. Biol. November 2004 24: 9568-9579; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Mre11 Nuclease Is Not Required for 5' to 3' Resection at Multiple HO-Induced Double-Strand Breaks Bertrand Llorente and Lorraine S. Symington Mol. Cell. Biol. November 2004 24: 9682-9694; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Gene Expression:

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Tumor Necrosis Factor Alpha Induction of NF-B Requires the Novel Coactivator SIMPL Hyung-Joo Kwon, Erin Haag Breese, Eva Vig-Varga, Yong Luo, Younghee Lee, Mark G. Goebl, and Maureen A. Harrington Mol. Cell. Biol. November 2004 24: 9317-9326; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interactions of Eukaryotic Translation Initiation Factor 3 (eIF3) Subunit NIP1/c with eIF1 and eIF5 Promote Preinitiation Complex Assembly and Regulate Start Codon Selection Leos Valásek, Klaus H. Nielsen, Fan Zhang, Christie A. Fekete, and Alan G. Hinnebusch Mol. Cell. Biol. November 2004 24: 9437-9455; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

CK2 Is Responsible for Phosphorylation of Human La Protein Serine-366 and Can Modulate rpL37 5'-Terminal Oligopyrimidine mRNA Metabolism Elena I. Schwartz, Robert V. Intine, and Richard J. Maraia Mol. Cell. Biol. November 2004 24: 9580-9591; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Both BC-Box Motifs of Adenovirus Protein E4orf6 Are Required To Efficiently Assemble an E3 Ligase Complex That Degrades p53 Paola Blanchette, Chi Ying Cheng, Qin Yan, Gary Ketner, David A. Ornelles, Thomas Dobner, Ronald C. Conaway, Joan Weliky Conaway, and Philip E. Branton Mol. Cell. Biol. November 2004 24: 9619-9629; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nuclear Pre-mRNA Decapping and 5' Degradation in Yeast Require the Lsm2-8p Complex Joanna Kufel, Cecile Bousquet-Antonelli, Jean D. Beggs, and David Tollervey Mol. Cell. Biol. November 2004 24: 9646-9657; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Transcriptional Regulation:

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Cofilin 1 Is Revealed as an Inhibitor of Glucocorticoid Receptor by Analysis of Hormone-Resistant Cells Joëlle Rüegg, Florian Holsboer, Christoph Turck, and Theo Rein Mol. Cell. Biol. November 2004 24: 9371-9382; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Yaf9 Component of the SWR1 and NuA4 Complexes Is Required for Proper Gene Expression, Histone H4 Acetylation, and Htz1 Replacement near Telomeres Haiying Zhang, Daniel O. Richardson, Douglas N. Roberts, Rhea Utley, Hediye Erdjument-Bromage, Paul Tempst, Jacques Côté, and Bradley R. Cairns Mol. Cell. Biol. November 2004 24: 9424-9436; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

The Proneural Proteins Atonal and Scute Regulate Neural Target Genes through Different E-Box Binding Sites Lynn M. Powell, Petra I. zur Lage, David R. A. Prentice, Biruntha Senthinathan, and Andrew P. Jarman Mol. Cell. Biol. November 2004 24: 9517-9526; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Recruitment of the Swi/Snf Complex by Ste12-Tec1 Promotes Flo8-Mss11-Mediated Activation of STA1 Expression Tae Soo Kim, Hye Young Kim, Jin Ho Yoon, and Hyen Sam Kang Mol. Cell. Biol. November 2004 24: 9542-9556; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

FoxA Proteins Regulate H19 Endoderm Enhancer E1 and Exhibit Developmental Changes in Enhancer Binding In Vivo Lingyun Long and Brett T. Spear Mol. Cell. Biol. November 2004 24: 9601-9609; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Characterization of a Trypanosoma brucei TATA-Binding Protein-Related Factor Points to a Universal Regulator of Transcription in Trypanosomes Jia-peng Ruan, George K. Arhin, Elisabetta Ullu, and Christian Tschudi Mol. Cell. Biol. November 2004 24: 9610-9618; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human SWI/SNF-Associated PRMT5 Methylates Histone H3 Arginine 8 and Negatively Regulates Expression of ST7 and NM23 Tumor Suppressor Genes Sharmistha Pal, Sheethal N. Vishwanath, Hediye Erdjument-Bromage, Paul Tempst, and Saïd Sif Mol. Cell. Biol. November 2004 24: 9630-9645; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

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Mammalian Genetic Models With Minimal Or Complex Phenotypes:

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p53 Deficiency Rescues Neuronal Apoptosis but Not Differentiation in DNA Polymerase ß-Deficient Mice Noriyuki Sugo, Naoko Niimi, Yasuaki Aratani, Keiko Takiguchi-Hayashi, and Hideki Koyama Mol. Cell. Biol. November 2004 24: 9470-9477; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Disruption of the Mouse mTOR Gene Leads to Early Postimplantation Lethality and Prohibits Embryonic Stem Cell Development Yann-Gaël Gangloff, Matthias Mueller, Stephen G. Dann, Petr Svoboda, Melanie Sticker, Jean-Francois Spetz, Sung Hee Um, Eric J. Brown, Silvia Cereghini, George Thomas, and Sara C. Kozma Mol. Cell. Biol. November 2004 24: 9508-9516; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.