Cover photograph (Copyright © 2004, American Society for Microbiology. All Rights Reserved.): PML body-specific repression of transcription by Bach2. GM02063 cells, a human fibroblast cell line, were transiently transfected with a FLAG-Bach2 expression plasmid. Upon oxidative stress, PML bodies (red) were completely surrounded by Bach2 (green), resulting in the selective repression of PML body-associated transcription activity (blue). (See related article on p. 3473.)