Cover photograph (Copyright © 2007, American Society for Microbiology. All Rights Reserved.): Colocalization of the epidermal growth factor-activated p90RSK1 (green) with the catalytic (red) and regulatory (blue) subunits of cyclic AMP-dependent protein kinase (PKA) in the nuclei of cells. Left panels show the colocalization of all three proteins (top), of p90RSK1 with the RI subunit of PKA (middle), and of p90RSK1 with the catalytic subunit of PKA (bottom). Right panels show that the colocalization of these proteins in the nucleus is abrogated by a peptide that disrupts the interactions of the regulatory subunit of PKA with PKA anchoring proteins. (See related article in June 2006, vol. 26: issue 12, p. 4586.)