Cover photograph (Copyright © 2007, American Society for Microbiology. All Rights Reserved.): Confocal images of Drosophila Schneider cells showing the localization of the P-body component Tral (homolog of human RAP55). The image shows that P-body number and size change dynamically in response to different cellular conditions. P bodies increase in size in cells overexpressing Stauffen (first row, left) or treated with puromycin (first row, right). P bodies are dispersed in cells depleted of Drosha (third row, left) or Ge-1 (third row, right). P-body size decreases in cells depleted of DCP1 (middle row, right). Middle row, left, wild-type cell. (See related article in June 2007, vol. 27: issue 11, p. 3970.)